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Clindamycin

CLINDAL CAPSULE

Regulatory Class: Rx
Generic Name: Clindamycin
Formulation/s: Each capsule contains 150 mg & 300 mg of Clindamycin (as hydrochloride), USP

Indications or Use: Clindal capsule is used for treatment of serious anaerobic infections especially those caused by Bacteroides fragilis. Alternative to penicillin in some severe Staph & Strep infections, including Staph osteomyelitis.

Dosage and Directions for Use: Adult Serious infections 300 mg every 6 hrs.

Administration: Take with or without food. Swallow whole w/ a full glass of water & in an upright position.

Contraindication: Hypersensitivity to lincomycin or clindamycin.

Special Precaution: Risk of antibiotic-associated colitis. Patients w/ history of GI disease especially colitis; renal or hepatic impairment. Perform periodic liver & kidney function tests during prolonged therapy (including neonate & infants). Prolonged treatment may result to superinfection. Atopic individuals.

Adverse Reaction: Nausea, vomiting, abdominal pain, diarrhea; transient neutropenia, eosinophilia, agranulocytosis, thrombocytopenia; pruritus, vaginitis; maculopapular rash, urticaria, generalized mild to moderate morbilliform-like skin rashes; jaundice & abnormalities in liver function tests

Interactions: May enhance action of other neuromuscular blockers. Antagonism w/ erythromycin (in vitro).

Presentation/ Packaging: Clindal capsule 50 mg x 100’s. 300 mg x 100’s.

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