Losartan Potassium
HYPERTHREE
Generic Name: Losartan Potassium
50 mg TABLET
ANGIOTENSIN II RECEPTOR BLOCKER
FORMULATION:
Each tablet contains………..50mg
INDICATION:
Losartan Potassium is used in the management of hypertension.
DOSAGE AND ADMINISTRATION → Dosage & Direction for Use
Usual dose is 50 mg once daily.
The dose may be increased, if necessary to 100 mg daily as a single dose or in two divided doses. An initial dose of 25 mg once daily may be used in the elderly over 75 years, and for patients with moderate to severe renal impairment (creatinine clearance less than 20 mL per minute), or intravascular fluid depletion.
A reduced dose should also be considered for patients with hepatic impairment.
Or as prescribed by a physician.
PRECAUTIONS:
Special Precaution
Losartan Potassium should be used with care, if at all, during breastfeeding. It should be used with caution in patients with renal artery stenosis. Reduced doses may be required in patients with renal or hepatic impairment. Patients with volume depletion may experience hypotension.
CONTRAINDICATION:
Losartan Potassium is contraindicated in pregnancy.
DRUG INTERACTIONS:
The antihypertensive effects of losartan may be potentiated by drugs or other agents that lower blood pressure. Additive hyperkalaemic effect is possible with potassium supplements, potassium-sparing diuretics, or other drugs that can cause hyperkalaemia, losartan and potassium-sparing diuretics should not generally be given together. NSAIDS should be used with caution in patients taking losartan as the risk of renal impairment may be increased particularly in those who are inadequately hydrated; use of NSAIDS may also attenuate the hypotensive effect of losartan,
ADVERSE EFFECTS: →adverse reaction
Adverse effects include dizziness and dose-related orthostatic hypotension. Hypotension may occur particularly in patients with volume depletion (for example those who have received high- dose diuretics). Losartan Potassium may cause hyperkalaemia in patients with renal disease. Other adverse effects that have been reported with angiotensin II receptor antagonist include respiratory tract disorder, back pain, gastrointestinal disturbances, fatigue, and neutropenia.
AVAILABILITY: →Packaging/ Presentation
White PVDC Blister pack x 10’s (Box of 100’s).
For more information, please see full product information.
